The lab is a government-financed research team. They work on identifying the causes and developing diagnosis and treatment methods of adult diseases and cancers.
At present, they are working on the discovery of genes that can maximize radiation therapy effect on cancer patients, the treatment techniques of metabolic diseases accompanied by obesity and other diseases, signal-transmitting systems related to insulin, and the discovery of Korean-specific SNP in osteoporosis genes and related gene discovery/ identification studies.
The lab carries out basic research in cell biology and immunology and runs the cell cultivation chamber and the flow cytometry.
The lab is working on disease development mechanism and regulation, molecular biological and cell biological research on the function, regulation and transmission agent of cure-related various cells. It is also actively engaging in the development of treatment techniques of metabolic diseases through the study of mitochondria functions, the study on the role of leukotactin-1, a new chemokine in rheumatic arthritis, the study on the role of HVEM and 4-1BB in allergic inflammation and airway remodeling of bronchial asthma airway and therapeutic possibility, and the study on surface antigen of cells related to diseases such as osteoporosis, diabetes, pulmonary fibrosis and nephritis, the study on adhesion protein and intracellular protein, the study on hematopoietic stem cell, the study on aging, the study on super antigen and self immune antigen, and the study on various tumor cell lines.
The laboratory is involved in developing the diagnosis, treatment and prevention methods of illnesses through the research on gene functions related to the identification of genetic causes using genomic analysis methods.
The Genome Research Center for Birth Defects and Genetic Disorders (www.amcgenome.org) designated by the Ministry of Health, Welfare and Family Affairs is working on the clinical applicability and the development of prevention methods by carrying out biological research on gene discovery and genetic mutation related to various genetic disorders and congenital heart defects of human
In addition, the center is equipped with an unparallel research environment where a group of clinical researchers conduct basic genome research and clinical research at the same time and the research findings are applied to the clinical trials. Such an effort will serve as a basis for realization of the personalized medicine based on individual genetic difference.
The laboratory is carrying out research to identify the pathophysiology of internal organs. It is also involved in the study on suppressing organ transplant rejection, insulin resistance treatment, islet autotransplantation, a single antigen synthesis of nucleroprotein, and the efficacy examination of new drugs in the animal models of heart disease and diabetes.
The laboratory has the first 4.7T MRI/MRS System for animal in Korea and employs the human in vivo MRS, animal in vivo MRS, in vitro NMR and the 3rd phase MRS in a mutually complementary way. It not only applies MRS using the 3D localization in brain, muscles, and heart by monitoring qualitative and quantitative analysis of bio metabolism but also uses T1 and T2 Weighted MRI and Micro MRI in picturing micro-structure of live tissues.
It has a SPF section, Semi-SPF section, Clean section, animal infection test section, operating room, electrophysiology room, SPF clearing chamber, transformation lab, microbiology lab, quarantine chamber, etc.
It can breed small to large-sized animals such as mice, rats, rabbits, dogs and pigs. It is working on technical support for animal tests and the study on the development and maintenance of transformed animals.
It runs the animal test committee to ensure the animal welfare and the ethics of animal testing.